Product description

Cell Xtreme is an advanced super-resolution platform combining fluorescence-based MI-SIM with label-free Optical Diffraction Tomography technology. This correlative approach combines the molecular specificity of fluorescence imaging with the complete spatial context provided by label-free imaging.

ODT reconstructs three-dimensional refractive index maps of living samples without fluorescent labels or damaging high-intensity illumination. Together with MI-SIM and AI-supported image segmentation, Cell Xtreme provides detailed information about cellular architecture, molecular targets and dynamic biological processes while maintaining cell viability.

Features

• Integrated MI-SIM and label-free ODT imaging
• Fluorescence super-resolution down to 60 nm
• Label-free tomographic resolution down to 130 nm
• Volumetric ODT imaging in less than one second
• No Z-stacking required for ODT volume acquisition
• Minimal phototoxicity for continuous long-term imaging
• AI segmentation of cellular structures
• Identification of nuclei, chromatin, nucleoli, lipid droplets and cell boundaries
• Multiplex imaging with fewer fluorescent labels
• Digital registration of SIM and ODT images
• Multi-site imaging and sample overview tools
• Intelligent event triggering and feedback microscopy
• Hybrid tracking using frequent ODT imaging and targeted SIM acquisition

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