geneMAP™ MTHFR C677T Mutation Detection Kit

geneMAP™ MTHFR C677T Mutation Detection Kit

$318.00

1 in stock

SKU: MTHFI-RT50 Category:

Description

The geneMAP™ MTHFR C677T Mutation Detection Kit is a rapid and accurate real-time PCR assay for the detection of the 677C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene. This mutation is associated with reduced enzyme activity leading to hyperhomocysteinemia and toxic side effects of methotrexate treatment. The kit is designed to identify patients predisposed to develop cardiovascular diseases or intolerance to methotrexate. 

Size: 50 tests

Product description

The geneMAP™ MTHFR C677T Mutation Detection Kit is a rapid and accurate real-time PCR assay for the detection of the 677C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene. This mutation is associated with reduced enzyme activity leading to hyperhomocysteinemia and toxic side effects of methotrexate treatment. The kit is designed to identify patients predisposed to develop cardiovascular diseases or intolerance to methotrexate. 

Size: 50 tests

Features

  • Easy to use with a ready-to-use reaction mix.
  • Delivers accurate results, including Homozygous and Heterozygous controls.
  • Compatible with dual-color real-time PCR instruments using FAM and VIC/HEX detection channels.
  • Provides precise results through the TaqMan probe-based allelic discrimination method.
  • CE-IVD
  • Real-time PCR

Specifications

Detection of the following SNPs and their corresponding normal alleles.

For the detection of the 677C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene.

 

CONTENTS 

C677T Master Mix – 850 µl

RNase Free Water – 400 µl

Positive Control (Heterozygous) – 100 µl

Positive Control (Homozygous)  – 100 µl

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