Product description

geneMAP™ MTHFR A1298C Mutation Detection Kit is a fast and accurate real-time PCR test for the detection of the 1298A>C mutation in the methylenetetrahydrofolate reductase (MTHFR) gene. The mutation is associated with decreased enzyme activity, which leads to hyperhomocysteinemia and to toxic side-effects of methotrexate therapy. The kit is designed to identify patients predisposed to develop cardiovascular diseases or intolerance to methotrexate.

Size: 50 tests

Features

• Easy to use with a ready-to-use reaction mix.
• Delivers accurate results, including Homozygous and Heterozygous controls.
• Compatible with dual-color real-time PCR instruments using FAM and VIC/HEX detection channels.
• Provides precise results through the TaqMan probe-based allelic discrimination method.
• CE-IVD
• Real-time PCR

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