Description
The geneMAP™ MTHFR C677T Mutation Detection Kit is a rapid and accurate real-time PCR assay for the detection of the 677C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene. This mutation is associated with reduced enzyme activity leading to hyperhomocysteinemia and toxic side effects of methotrexate treatment. The kit is designed to identify patients predisposed to develop cardiovascular diseases or intolerance to methotrexate.
Size: 50 tests
Product description
The geneMAP™ MTHFR C677T Mutation Detection Kit is a rapid and accurate real-time PCR assay for the detection of the 677C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene. This mutation is associated with reduced enzyme activity leading to hyperhomocysteinemia and toxic side effects of methotrexate treatment. The kit is designed to identify patients predisposed to develop cardiovascular diseases or intolerance to methotrexate.
Size: 50 tests
Features
- Easy to use with a ready-to-use reaction mix.
- Delivers accurate results, including Homozygous and Heterozygous controls.
- Compatible with dual-color real-time PCR instruments using FAM and VIC/HEX detection channels.
- Provides precise results through the TaqMan probe-based allelic discrimination method.
- CE-IVD
- Real-time PCR
Specifications
Detection of the following SNPs and their corresponding normal alleles.
For the detection of the 677C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene.
CONTENTS
C677T Master Mix – 850 µl
RNase Free Water – 400 µl
Positive Control (Heterozygous) – 100 µl
Positive Control (Homozygous) – 100 µl










