geneMAP™ JAK-2 Exon 12 Mutations Detection Kit
$843.20
1 in stock
Description
Approximately 95% of Polycythemia Vera patients are positive for JAK2 mutation (exon 14) and only 5% are positive for JAK2 exon 12 mutation. JAK2 and other mutation screening tests are often ordered if the clinical findings support PV or other myeloproliferative neoplasms (MPN). The geneMAP™ JAK-2 Exon12 Mutations Detection Kit is intended for the detection and quantification of 10 mutations in JAK2 exon 12 location from DNA extracted from peripheral blood. These mutations; N542-E543del, E543-D544del, K539L, H538-K539delinsL, I540-E543delinsMK, H538QK539L, R541-E543de- linsK, F537-K539delinsL, V536-I546dup11, F537-I540delinsLV
Size: 50 tests
Related products
Product description
Approximately 95% of Polycythemia Vera patients are positive for JAK2 mutation (exon 14) and only 5% are positive for JAK2 exon 12 mutation. JAK2 and other mutation screening tests are often ordered if the clinical findings support PV or other myeloproliferative neoplasms (MPN). The geneMAP™ JAK-2 Exon12 Mutations Detection Kit is intended for the detection and quantification of 10 mutations in JAK2 exon 12 location from DNA extracted from peripheral blood. These mutations; N542-E543del, E543-D544del, K539L, H538-K539delinsL, I540-E543delinsMK, H538QK539L, R541-E543de- linsK, F537-K539delinsL, V536-I546dup11, F537-I540delinsLV
Size: 50 tests
Features
- Quantification and detection of 10 mutations in JAK2 exon 12.
- Superior analytical sensitivity and specifity with Allele Spesfic PCR.
- Fast and Easy use with Multiplex Realtime PCR Technology.
- Limit of Detection 0.5 %, with a 95% confidence
- Automatic analysis with geneMAP™ viewer (for CFX96™ / BIO-RAD).
- CE-IVD
- Real-time PCR
