Product description

The geneMAP™ HLA-B*57:01 Detection Kit is a rapid and accurate real-time PCR test for detecting the HLA-B*57:01 allele, a specific variant of the human leukocyte antigen B (HLA-B) gene strongly associated with abacavir hypersensitivity.

Abacavir, a nucleoside reverse transcriptase inhibitor, is used in combination antiretroviral therapy for treating HIV infecti- on. However, abacavir can cause a severe and potentially life-threatening hypersensitivity reaction, which limits its use. This reaction is strongly linked to the presence of the HLA-B*57:01 allele. Screening for HLA-B*57:01 can help clinicians identify patients at risk of experiencing abacavir-induced hypersensitivity, ensuring safer treatment decisions.

Size: 25 tests

Features

• Fast and easy to use with advanced qPCR technology.
• Simple screening of patients for the HLA-B*57:01 allele before initiating abacavir treatment.
• Compatible with dual-color real-time PCR instruments using FAM and VIC/HEX channels.
• CE-IVD
• Real-time PCR

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