Acute Myeloid Leukemia (AML) is the most common form of leukemia in adults and FLT3 activating mutations are expected to be present in 1 in 3 people diagnosed with AML. The presence of FLT3 activating mutations in AML indicates a poor prognosis and some treatment regimens and targeted drug trials are only accessible to patients… Continue reading geneMAP™ FLT3 ITD/D835Y Mutation Detection Kit
The geneMAP™ FMF 11 Mutation Detection Kit is a reliable real-time PCR test designed to detect the 11 most common genetic mutations associated with Familial Mediterranean Fever (FMF) in a simple and efficient multiplex format. FMF is a hereditary disorder most prevalent among Jewish, Turkish, Middle Eastern Arab, Armenian, and Japanese populations. It is characterized… Continue reading geneMAP™ FMF 11 Mutation Detection Kit
The geneMAP™ FMF 5 Mutation Detection Kit is a simple and efficient real-time PCR test for identifying the 5 most common genetic mutations associated with Familial Mediterranean Fever (FMF) in a multiplex format. FMF is a hereditary disorder chara- cterized by recurrent episodes of fever, abdominal pain, chest pain, and joint pain, lasting 24-48 hours.… Continue reading geneMAP™ FMF 5 Mutation Detection Kit
The geneMAP™ FV Leiden Mutation Detection Kit is a rapid and accurate real-time PCR test for the detection of the 1691G>A mutation in the human coagulation Factor V (F5) gene. The FV Leiden mutation is associated with inherited thrombophilia. The kit is designed to identify patients at risk of venous thromboembolism. 20-50% of patients with… Continue reading geneMAP™ FV Leiden Mutation Detection Kit
The geneMAP™ FXIII Mutation Detection Kit is a fast and accurate real-time PCR test for the detection of a G>T transition in exon 2 of the human coagulation Factor XIII (F13A) gene. This polymorphism leads to a valine (V) to leucine (L) substitution at amino acid 34 of the FXIII subunit A. The L variant… Continue reading geneMAP™ FXIII Mutation Detection Kit
The geneMAP™ HER-2 Expression Analysis Kit is intended for the relative quantitation of HER-2 transcripts in human tumor cells. Size: 24 tests
The geneMAP™ HLA-B*27 Detection Kit, discriminates the presence or absence of HLAB*27 alleles in a human genomic DNA extract from blood and detects the majority of diseaserelevant HLA-B*27 subtypes. HLA-B*27 is a genetic risk factor for seronegative spondyloarthropathies, such asankylosing spondylitis, reactive arthritis, juvenile rheumatoid arthritis and anterior uveitis. Size: 50 tests
The HLA-B*51 allele, a class I human leukocyte antigen (HLA) molecule, is the strongest known genetic risk factor for Behçet’s Disease (BD). The geneMAP™ HLA-B*51 Detection Kit is designed to detect the presence of the most common HLA-B*51 allele in human genomic DNA. Size: 50 tests
The geneMAP™ HLA-B*57:01 Detection Kit is a rapid and accurate real-time PCR test for detecting the HLA-B*57:01 allele, a specific variant of the human leukocyte antigen B (HLA-B) gene strongly associated with abacavir hypersensitivity. Abacavir, a nucleoside reverse transcriptase inhibitor, is used in combination antiretroviral therapy for treating HIV infecti- on. However, abacavir can cause… Continue reading geneMAP™ HLA-B*57:01 Detection Kit
The geneMAP™ HPV 29 Genotyping Kit is a semi qualitative in vitro assay for detection and genotyping of 29 High Risk and Low Risk Human Papilloma Viruses (HPV16, HPV18, HPV26, HPV31, HPV33, HPV35, HPV39, HPV40, HPV42, HPV43, HPV44, HPV45, HPV51, HPV52, HPV53, HPV54, HPV56, HPV58, HPV59, HPV61, HPV66, HPV68, HPV69, HPV70, HPV73, HPV81/82 and HPV6/11)… Continue reading geneMAP™ HPV 29 Genotyping Kit
The geneMAP™ HPV HR & 6 /11 Genotyping Kit is a semi qualitative in vitro assay for detection and genotyping of 14 High Risk and 2 Low Risk Human Papilloma Virus (HPV16, HPV18, HPV31, HPV33, HPV35, HPV39, HPV45, HPV51, HPV52, HPV56, HPV58, HPV59, HPV66, HPV68 and HPV6/11) from fresh tissue, FFPE tissue, buccal swab, cervical… Continue reading geneMAP™ HPV HR & 6 /11 Genotyping Kit
The geneMAP™ IDH1/2 Mutations Detection Kit R132L, R132V, R132G, R132S, R132H, R132C, R132P, R100Q, R140G, R140L, R140W, R140Q, R172S, R172K, R172W, R172M, R172G mutations on IDH1/2 genes. Size: 25 tests
Approximately 95% of Polycythemia Vera patients are positive for JAK2 mutation (exon 14) and only 5% are positive for JAK2 exon 12 mutation. JAK2 and other mutation screening tests are often ordered if the clinical findings support PV or other myeloproliferative neoplasms (MPN). The geneMAP™ JAK-2 Exon12 Mutations Detection Kit is intended for the detection… Continue reading geneMAP™ JAK-2 Exon 12 Mutations Detection Kit
The geneMAP™ MGMT Methylation Analysis Kit is a methylation-specific Realtime PCR (MSP) test designed to detect and quan- tification O (6) -methylguanine-DNA methyltransferase (MGMT) promoter hypermethylation status in genomic DNA of glioblas- toma multiform (GBM) tumors. MGMT promoter methylation has been shown to lead to increased sensitivity to alkylating agents such as temozolomide and to… Continue reading geneMAP™ MGMT Methylation Analysis Kit
The geneMAP™ MLH1 Methylation Analysis Kit is a methylation-specific Realtime PCR (MSP) test designed to detect and quan- tification MutL homolog 1 (MLH1) gene promoter hypermethylation status in genomic DNA of FFPE tissues. Size: 50 tests